Las Plagas came into play in a similar fashion: as the fable of climate change miraculously becomes reality, bacteria and viruses long-trapped in ice, are coming back to life as they are being melted free

Now I don’t want to get too political and be all like see, this is why climate change is a real thing, but this is pretty much the plot to Resident Evil 4, and all subsequent Resident Evil games that utilized Las Plagas.  But instead of evil Umbrella/whatever evil corporation actively digging and seeking out long-dormant bacteria and viruses, in this case it’s kind of scarier in the sense that it’s not being controlled by man, but are kind of unveiling themselves discreetly and unaccounted for on their own by virtue of being melted out of whatever frozen confinement that had been keeping them locked away for however long they’ve been out of play.

Sure, it’s starting with strains of anthrax, smallpox and the Spanish flu revealing themselves from melted graves, but at this rate, one of these days it’s only a matter of time when the real Las Plagas parasites melt their way out of rural Spain and begin infesting in modern humanity leading to the eventual downfall of mankind.  The difference is that Leon Kennedy, Chris Redfield and Jill Valentine don’t actually exist, but there are very much crooked corporations like Umbrella out there that would gladly nefariously try to weaponize and control such terrible things.

I’m just saying, this is pretty much the backstory to the plot of Resident Evil 4, and if Ivanka goes missing while on a humanitarian appearance/fashion show out in Europe, then fiction will have a pretty scary time becoming an action-packed reality.  The real-life Leon Kennedy better start training up for his eventual mission of saving the world.